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1

Pharmacodynamic and pharmacokinetic effects and safety of verinurad in combination with allopurinol in adults with gout: a phase IIa, open-label study

Fleischmann, Roy, Winkle, Peter, Miner, Jeffrey N, Yan, Xiaohong, Hicks, Liz, Valdez, Shakti, Hall, Jesse, Liu, Sha, Shen, Zancong, Gillen, Michael, Hernandez-Illas, Martha

Journal:

Year:

2018

Language:

english

File:

PDF, 1.31 MB

english, 2018

2

Clinical Communication: Systemic Capillary Leak Syndrome Due to Mast Cell Activation?

Van Winkle, Robert C., Malatack, J. Jeffrey, Schwartz, Lawrence B., McGeady, Stephen J.

Journal:

Annals of Allergy, Asthma & Immunology

Year:

2019

Language:

english

File:

PDF, 347 KB

english, 2019

3

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - San Diego, California, USA (Sunday 27 June 2010)] Millimeter, Submillimeter, and Far-Infrared Detectors and Instrumentation for Astronomy V - Development of MMIC receivers for cosmic microwave background interferometry

Sieth, Matthew, Holland, Wayne S., Zmuidzinas, Jonas, Lau, Judy M., Voll, Patricia, Church, Sarah, Kangaslahti, Pekka, Samoska, Lorene, Soria, Mary, Gaier, Todd, Van Winkle, Dan, Neilson, Jeffrey, Tan

Year:

2010

Language:

english

File:

PDF, 10.43 MB

english, 2010

4

Fibroblast growth factor-1-inducible gene FR-17 encodes a nonmuscle α-actinin isoform

Debbie K.W. Hsu, Yan Guo, Gregory F. Alberts, Kimberly A. Peifley, Jeffrey A. Winkles

Journal:

Journal of Cellular Physiology

Year:

1996

Language:

english

File:

PDF, 1.38 MB

english, 1996

5

Differential expression of the keratinocyte growth factor (KGF) and KGF receptor genes in human vascular smooth muscle cells and arteries

Jeffrey A. Winkles, Gregory F. Alberts, Marcio Chedid, William G. Taylor, Sabina DeMartino, Jeffrey S. Rubin

Journal:

Journal of Cellular Physiology

Year:

1997

Language:

english

File:

PDF, 148 KB

english, 1997

6

Progressive ankylosis protein (ANK) in osteoblasts and osteoclasts controls bone formation and bone remodeling

Hyon Jong Kim, Takeshi Minashima, Edward F McCarthy, Jeffrey A Winkles, Thorsten Kirsch

Journal:

Journal of Bone and Mineral Research

Year:

2010

Language:

english

File:

PDF, 614 KB

english, 2010

7

Polypeptide growth factors and phorbol ester induce progressive ankylosis (Ank) gene expression in murine and human fibroblasts

Yan Guo, Debbie K.W. Hsu, Sheau-Line Y. Feng, Christine M. Richards, Jeffrey A. Winkles

Journal:

Journal of Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 242 KB

english, 2002

8

Structure-function studies of heparin-binding (acidic fibroblast) growth factor-1 using site-directed mutagenesis

Wilson H. Burgess, Anne M. Shaheen, Brian Hampton, Patrick J. Donohue, Jeffrey A. Winkles

Journal:

Journal of Cellular Biochemistry

Year:

1991

Language:

english

File:

PDF, 820 KB

english, 1991

9

Altered regulation of platelet-derived growth factor A-chain and c-fos gene expression in senescent progeria fibroblasts

Jeffrey A. Winkles, Mary L. O'Connor, Robert Friesel

Journal:

Journal of Cellular Physiology

Year:

1990

Language:

english

File:

PDF, 1.60 MB

english, 1990

10

The half-lives of platelet-derived growth factor A- and B-chain mRNAS are similar in endothelial cells and unaffected by heparin-binding growth factor-1 or cycloheximide

Cyril G. Gay, Jeffrey A. Winkles

Journal:

Journal of Cellular Physiology

Year:

1991

Language:

english

File:

PDF, 807 KB

english, 1991

11

Efficacy and Toxicity of Intracavitary Administration of Pegylated Liposomal Encapsulated Doxorubicin (DOXIL) in Dogs with Hemangiosarcoma

Karin Sorenmo, Marissa Samluk, Craig Clifford, Jennifer Baez, Beth Overley, Katherine Skorupski, Karen Oberthaler, Jeffrey Barrett, Tom Van Winkle, Gabriela Seiler, Robert Poppenga, Frances Shofer

Journal:

Veterinary and Comparative Oncology

Year:

2005

Language:

english

File:

PDF, 196 KB

english, 2005

12

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

Winkles, Jeffrey A.

Journal:

Nature Reviews Drug Discovery

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

13

TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration

Girgenrath, Mahasweta, Weng, Shawn, Kostek, Christine A, Browning, Beth, Wang, Monica, Brown, Sharron AN, Winkles, Jeffrey A, Michaelson, Jennifer S, Allaire, Norm, Schneider, Pascal

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 626 KB

english, 2006

14

TWEAK–Fn14 pathway inhibition protects the integrity of the neurovascular unit during cerebral ischemia

Zhang, Xiaohui, Winkles, Jeffrey A, Gongora, Maria C, Polavarapu, Rohini, Michaelson, Jennifer S, Hahm, Kyungmin, Burkly, Linda, Friedman, Meyer, Li, Xiao-Jiang, Yepes, Manuel

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2006

Language:

english

File:

PDF, 243 KB

english, 2006

15

Differential regulation of polo-like kinase 1, 2, 3, and 4 gene expression in mammalian cells and tissues

Winkles, Jeffrey A, Alberts, Gregory F

Journal:

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

16

Structure-function studies of FGF-1: Dissociation and partial reconstitution of certain of its biological activities

Wilson H. Burgess, Robert Friesel, Jeffrey A. Winkles

Journal:

Molecular Reproduction and Development

Year:

1994

Language:

english

File:

PDF, 909 KB

english, 1994

17

Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes

Horace T. B. Ho, Nancy A. Jenkins, Neal G. Copeland, Debra J. Gilbert, Jeffrey A. Winkles, Helena W. Y. Louie, Fuk K. Lee, Stephen S. M. Chung, Sookja K. Chung

Journal:

Year:

1999

Language:

english

File:

PDF, 675 KB

english, 1999

18

Angiotensin II and Endothelin-1 Increase Fibroblast Growth Factor-2 mRNA Expression in Vascular Smooth Muscle Cells

Kimberly A. Peifley, Jeffrey A. Winkles

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.28 MB

english, 1998

19

Primary Structure of Ovine Fibroblast Growth Factor-1 Deduced by Protein and cDNA Analysis

Teri Wangler Grieb, Mary Ring, Ernest Brown, Carol Palmer, Natalie Belle, Dubravka Donjerkovic, Helena Chang, June Yun, Ramiah Subramanian, Farahnaz Forozan, Yan Guo, Akos Vertes, Jeffrey A. Winkles,

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 2.45 MB

english, 1998

20

Fibroblast Growth Factor-1 Induction of Delayed-Early mRNA Expression in NIH 3T3 Cells Is Prolonged by Heparin Addition

Patrick J. Donohue, Debbie K.W. Hsu, Yan Guo, Wilson H. Burgess, Jeffrey A. Winkles

Journal:

Experimental Cell Research

Year:

1997

Language:

english

File:

PDF, 359 KB

english, 1997

21

FGF-1 Affixation Stimulates ePTFE Endothelialization without Intimal Hyperplasia

John L. Gray, Steven S. Kang, Gregory C. Zenni, Dae Un Kim, Peter I. Kim, Wilson H. Burgess, William Drohan, Jeffrey A. Winkles, Christian C. Haudenschild, Howard P. Greisler

Journal:

Journal of Surgical Research

Year:

1994

File:

PDF, 3.95 MB

1994

22

Clinical electrophysiologic effects of tocainide

Jeffrey L. Anderson, Jay W. Mason, Roger A. Winkle, Peter J. Meffin, Robert E. Fowles, Flora Peters, Donald C. Harrison

Journal:

The American Journal of Cardiology

Year:

1978

Language:

english

File:

PDF, 143 KB

english, 1978

23

Accumulation and decay of DG42 gene products follow a gradient pattern during Xenopus embryogenesis

Frédéric Rosa, Thomas D. Sargent, Martha L. Rebbert, George S. Michaels, Milan Jamrich, Horst Grunz, Erzsebet Jonas, Jeffrey A. Winkles, Igor B. Dawid

Journal:

Developmental Biology

Year:

1988

Language:

english

File:

PDF, 4.38 MB

english, 1988

24

TWEAK and Fn14: New molecular targets for cancer therapy?

Jeffrey A. Winkles, Nhan L. Tran, Michael E. Berens

Journal:

Year:

2006

Language:

english

File:

PDF, 165 KB

english, 2006

25

A Soluble Fn14-Fc Decoy Receptor Reduces Infarct Volume in a Murine Model of Cerebral Ischemia

Manuel Yepes, Sharron A.N. Brown, Elizabeth G. Moore, Elizabeth P. Smith, Daniel A. Lawrence, Jeffrey A. Winkles

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 1.33 MB

english, 2005

26

The Human Fn14 Receptor Gene Is Up-Regulated in Migrating Glioma Cells in Vitro and Overexpressed in Advanced Glial Tumors

Nhan L. Tran, Wendy S. McDonough, Patrick J. Donohue, Jeffrey A. Winkles, Theresa J. Berens, Kristen R. Ross, Dominique B. Hoelzinger, Christian Beaudry, Stephen W. Coons, Michael E. Berens

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 631 KB

english, 2003

27

The Fn14 Immediate-Early Response Gene Is Induced During Liver Regeneration and Highly Expressed in Both Human and Murine Hepatocellular Carcinomas

Sheau-Line Y. Feng, Yan Guo, Valentina M. Factor, Snorri S. Thorgeirsson, Daphne W. Bell, Joseph R. Testa, Kimberly A. Peifley, Jeffrey A. Winkles

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 1.08 MB

english, 2000

28

Regulated expression of PDGF A-chain mRNA in human saphenous vein smooth muscle cells

Jeffrey A. Winkles, Cyril G. Gay

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 728 KB

english, 1991

29

130 Characterization of a novel endothelial receptor, LR3, that defines a new class of receptors related to the LDL receptor family

Todd A. Hembrough, Frances D. Battey, Jeffrey A. Winkles, Dudley K. Strickland

Journal:

Fibrinolysis and Proteolysis

Year:

1997

Language:

english

File:

PDF, 113 KB

english, 1997

30

TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor

Steven R Wiley, Jeffrey A Winkles

Journal:

Cytokine & Growth Factor Reviews

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

31

Clinical and Pharmacokinetic Characteristics of Intracavitary Administration of Pegylated Liposomal Encapsulated Doxorubicin in Dogs with Splenic Hemangiosarcoma

Karin Sorenmo, Marissa Samluk, Craig Clifford, Jennifer Baez, Jeffrey S. Barrett, Robert Poppenga, Beth Overley, Katherine Skorupski, Karen Oberthaler, Tom Van Winkle, Gabriela Seller, Frances Shofer

Journal:

Journal of Veterinary Internal Medicine

Year:

2007

Language:

english

File:

PDF, 391 KB

english, 2007

32

Polyadenylation state of abundant mRNAs during Drosophila development

Jeffrey A. Winkles, Robert M. Grainger

Journal:

Developmental Biology

Year:

1985

Language:

english

File:

PDF, 3.58 MB

english, 1985

33

A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis

Steven R Wiley, Linda Cassiano, Timothy Lofton, Terry Davis-Smith, Jeffrey A Winkles, Volkhard Lindner, Hua Liu, Thomas O Daniel, Craig A Smith, William C Fanslow

Journal:

Year:

2001

Language:

english

File:

PDF, 643 KB

english, 2001

34

Molecular pathways triggering glioma cell invasion

Salhia, Bodour, Tran, Nhan L, Symons, Marc, Winkles, Jeffrey A, Rutka, James T, Berens, Michael E

Journal:

Expert Review of Molecular Diagnostics

Year:

2006

Language:

english

File:

PDF, 1.63 MB

english, 2006

35

Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential

Wang, Xiang, Ji, Zhaoxia, Chang, Chong Hyun, Zhang, Haiyuan, Wang, Meiying, Liao, Yu-Pei, Lin, Sijie, Meng, Huan, Li, Ruibin, Sun, Bingbing, Winkle, Laura Van, Pinkerton, Kent E., Zink, Jeffrey I., Xi

Journal:

Year:

2014

Language:

english

File:

PDF, 4.17 MB

english, 2014

36

Human Vascular Smooth Muscle Cells Both Express and Respond to Heparin-Binding Growth Factor I (Endothelial Cell Growth Factor)

Jeffrey A. Winkles, Robert Friesel, Wilson H. Burgess, Richard Howk, Tevie Mehlman, Robert Weinstein and Thomas Maciag

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 1.06 MB

english, 1987

37

Part 1 || Stage-Specific Keratins in Xenopus laevis Embryos and Tadpoles: The XK81 Gene Family

Seiji Miyatani, Jeffrey A. Winkles, Thomas D. Sargent and Igor B. Dawid

Journal:

The Journal of Cell Biology

Year:

1986

Language:

english

File:

PDF, 1.92 MB

english, 1986

38

Part 1 || Differential Stability of Drosophila Embryonic mRNAs during Subsequent Larval Development

Jeffrey A. Winkles and Robert M. Grainger

Journal:

The Journal of Cell Biology

Year:

1985

Language:

english

File:

PDF, 2.50 MB

english, 1985

39

Pseudomonas Exotoxin-Mediated Selection Yields Cells with Altered Expression of Low-Density Lipoprotein Receptor-Related Protein

David J. FitzGerald, Charlotte M. Fryling, Alexey Zdanovsky, Catharine B. Saelinger, Maria Kounnas, Jeffrey A. Winkles, Dudley Strickland and Stephen Leppla

Journal:

The Journal of Cell Biology

Year:

1995

Language:

english

File:

PDF, 1.01 MB

english, 1995

40

Part 1 || Possible Dissociation of the Heparin-Binding and Mitogenic Activities of Heparin-Binding (Acidic Fibroblast) Growth Factor-1 from Its Receptor-Binding Activities by Site-Directed Mutagenesis of a Single Lysine Residue

Wilson H. Burgess, Anne M. Shaheen, Mark Ravera, Michael Jaye, Patrick J. Donohue and Jeffrey A. Winkles

Journal:

The Journal of Cell Biology

Year:

1990

Language:

english

File:

PDF, 2.97 MB

english, 1990

41

Antiarrhythmic Drugs: Clinical Pharmacology and Therapeutic Uses

Jeffrey L. Anderson,Donald C. Harrison,Peter J. Meffin,Dr Roger A. Winkle

Journal:

Year:

1978

Language:

english

File:

PDF, 2.93 MB

english, 1978

42

Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells

Schneider, Craig S., Perez, Jimena G., Cheng, Emily, Zhang, Clark, Mastorakos, Panagiotis, Hanes, Justin, Winkles, Jeffrey A., Woodworth, Graeme F., Kim, Anthony J.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

43

Human fibroblast growth factor 1 gene expression in vascular smooth muscle cells is modulated via an alternate promoter in response to serum and phorbol ester

Chotani, Maqsood A., Payson, Robert A., Winkles, Jeffrey A., Chiu, Ing-Ming

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 7.66 MB

english, 1995

44

Progressive Ankylosis Gene (ank) Regulates Osteoblast Differentiation

Kirsch, Thorsten, Kim, Hyon Jong, Winkles, Jeffrey A.

Journal:

Cells Tissues Organs

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

45

TWEAK/Fn14 Axis-Targeted Therapeutics: Moving Basic Science Discoveries to the Clinic

Cheng, Emily, Armstrong, Cheryl L., Galisteo, Rebeca, Winkles, Jeffrey A.

Journal:

Frontiers in Immunology

Year:

2013

Language:

english

File:

PDF, 764 KB

english, 2013

46

Surface plasmon resonance as a high throughput method to evaluate specific and non-specific binding of nanotherapeutics

Schneider, Craig S., Bhargav, Adip G., Perez, Jimena G., Wadajkar, Aniket S., Winkles, Jeffrey A., Woodworth, Graeme F., Kim, Anthony J.

Journal:

Journal of Controlled Release

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

47

Interleukin 1 Regulates Heparin-Binding Growth Factor 2 Gene Expression in Vascular Smooth Muscle Cells

Cyril G. Gay and Jeffrey A. Winkles

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.12 MB

english, 1991

48

Murine FGF-Inducible Kinase is Rapidly Degraded via the Nuclear Ubiquitin-Proteosome System When Overexpressed in NIH 3T3 Cells

Alberts, Gregory F., Winkles, Jeffrey A.

Journal:

Year:

2004

Language:

english

File:

PDF, 624 KB

english, 2004

49

Letters to the Editor

Eric McHenry, Barbara Bates, Jack Labusch, Jay Robinson, Robert Daseler, Bill Daugherty, Deena Hardin, Mike Van Winkle, Mark Soifer, Jeffrey Shotts, Margaret Blaker, Karie Friedman and Rob Sayre

Journal:

Year:

2005

Language:

english

File:

PDF, 637 KB

english, 2005

50

CSIG-13INVESTIGATING THE ROLE OF Fn14 IN EGFRvIII-DRIVEN GLIOBLASTOMA

Roos, Alison, Mayo, Zach, Pineda, Michael, Winkles, Jeffrey A., Berens, Michael E., Tran, Nhan L.

Journal:

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015

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